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The son of a goldsmith, Sperandio was the most prolific fifteenth-century medalist. Born in Mantua, he is first noted in 1445 as a goldsmith in Ferrara. Later he worked in Faenza (1477), Bologna (1478-90), and Venice, as well as in Ferrara and Mantua. He was noted as a goldsmith, architect, sculptor and cannon-founder. A strong portraitist, but sometimes a careless medalist, his oeuvre is unusually well defined. See Forrer 5, pp. 583-97; Corpus, pp. 89-103; Hill in Thieme-Becker 31, pp. 359-60; Kress, pp. 26-28.